Opening task manager revealed a hidden IE or Firefox running. Kill the Process, it stops but hours later or the next day it would do the same thing. It sounds like movie clips not ads or commercials.
Fast Forward to my problem. My laptop has started doing it also. First time tonight. I think it may have invaded me over the network as I was not on any odd site and had not downloaded anything. I was admin logged into my website, building a page. I killed Firefox and it stopped, like an idiot, I did not even think to see if his PC was also playing it.
What is with all the (file missing) at the end of the string? 
Thank you for listening, here is my HJT Log
Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 4:51:37 AM, on 3/17/2009
Platform: Windows Vista SP1 (WinNT 6.00.1905)
MSIE: Internet Explorer v7.00 (7.00.6001.18000)
Boot mode: Normal
Running processes:
c:\PROGRA~2\mcafee.com\agent\mcagent.exe
C:\Program Files (x86)\Intel\Intel Matrix Storage Manager\IAAnotif.exe
C:\Program Files\CyberLink\PowerDVD DX\PDVDDXSrv.exe
C:\Program Files (x86)\Adobe\Adobe Photoshop CS3\Photoshop.exe
C:\Program Files (x86)\Trend Micro\thishijack\HijackThis.exe
C:\Program Files (x86)\Mozilla Firefox\firefox.exe
C:\PROGRA~2\MICROS~2\Office12\OUTLOOK.EXE
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant =
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,CustomizeSearch =
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = *.local
R0 - HKCU\Software\Microsoft\Internet Explorer\Toolbar,LinksFolderName =
F2 - REG:system.ini: UserInit=userinit.exe
O1 - Hosts: ::1 localhost
O2 - BHO: AcroIEHelperStub - {18DF081C-E8AD-4283-A596-FA578C2EBDC3} - c:\Program Files (x86)\Common Files\Adobe\Acrobat\ActiveX\AcroIEHelperShim.dll
O2 - BHO: McAfee Phishing Filter - {27B4851A-3207-45A2-B947-BE8AFE6163AB} - c:\PROGRA~2\mcafee\msk\mskapbho.dll
O2 - BHO: Groove GFS Browser Helper - {72853161-30C5-4D22-B7F9-0BBC1D38A37E} - C:\PROGRA~2\MICROS~2\Office12\GRA8E1~1.DLL
O2 - BHO: Java(tm) Plug-In SSV Helper - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files (x86)\Java\jre6\bin\ssv.dll
O2 - BHO: scriptproxy - {7DB2D5A0-7241-4E79-B68D-6309F01C5231} - C:\Program Files (x86)\McAfee\VirusScan\scriptsn.dll
O2 - BHO: McAfee SiteAdvisor BHO - {B164E929-A1B6-4A06-B104-2CD0E90A88FF} - c:\PROGRA~2\mcafee\SITEAD~1\mcieplg.dll
O2 - BHO: Browser Address Error Redirector - {CA6319C0-31B7-401E-A518-A07C3DB8F777} - C:\Program Files (x86)\Dell\BAE\BAE.dll
O2 - BHO: Java(tm) Plug-In 2 SSV Helper - {DBC80044-A445-435b-BC74-9C25C1C588A9} - C:\Program Files (x86)\Java\jre6\bin\jp2ssv.dll
O3 - Toolbar: McAfee SiteAdvisor Toolbar - {0EBBBE48-BAD4-4B4C-8E5A-516ABECAE064} - c:\PROGRA~2\mcafee\SITEAD~1\mcieplg.dll
O4 - HKLM\..\Run: [SunJavaUpdateSched] "C:\Program Files (x86)\Java\jre6\bin\jusched.exe"
O4 - HKLM\..\Run: [Adobe Reader Speed Launcher] "c:\Program Files (x86)\Adobe\Reader 9.0\Reader\Reader_sl.exe"
O4 - HKLM\..\Run: [PDVDDXSrv] "C:\Program Files\CyberLink\PowerDVD DX\PDVDDXSrv.exe"
O4 - HKLM\..\Run: [mcagent_exe] "C:\Program Files (x86)\McAfee.com\Agent\mcagent.exe" /runkey
O4 - HKLM\..\Run: [McENUI] C:\PROGRA~2\McAfee\MHN\McENUI.exe /hide
O4 - HKLM\..\Run: [GrooveMonitor] "C:\Program Files (x86)\Microsoft Office\Office12\GrooveMonitor.exe"
O4 - HKCU\..\Run: [Sidebar] C:\Program Files\Windows Sidebar\sidebar.exe /autoRun
O4 - HKCU\..\Run: [DAEMON Tools Lite] "C:\Program Files (x86)\DAEMON Tools Lite\daemon.exe" -autorun
O4 - HKCU\..\Run: [WMPNSCFG] C:\Program Files (x86)\Windows Media Player\WMPNSCFG.exe
O4 - HKUS\S-1-5-19\..\Run: [Sidebar] %ProgramFiles%\Windows Sidebar\Sidebar.exe /detectMem (User 'LOCAL SERVICE')
O4 - HKUS\S-1-5-19\..\Run: [WindowsWelcomeCenter] rundll32.exe oobefldr.dll,ShowWelcomeCenter (User 'LOCAL SERVICE')
O4 - HKUS\S-1-5-20\..\Run: [Sidebar] %ProgramFiles%\Windows Sidebar\Sidebar.exe /detectMem (User 'NETWORK SERVICE')
O4 - .DEFAULT User Startup: Dell Dock First Run.lnk = C:\Program Files\Dell\DellDock\DellDock.exe (User 'Default user')
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~2\MICROS~2\Office12\EXCEL.EXE/3000
O9 - Extra button: Send to OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\PROGRA~2\MICROS~2\Office12\ONBttnIE.dll
O9 - Extra 'Tools' menuitem: S&end to OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\PROGRA~2\MICROS~2\Office12\ONBttnIE.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~2\MICROS~2\Office12\REFIEBAR.DLL
O13 - Gopher Prefix:
O18 - Protocol: grooveLocalGWS - {88FED34C-F0CA-4636-A375-3CB6248B04CD} - C:\PROGRA~2\MICROS~2\Office12\GR99D3~1.DLL
O18 - Protocol: sacore - {5513F07E-936B-4E52-9B00-067394E91CC5} - c:\PROGRA~2\mcafee\SITEAD~1\mcieplg.dll
O23 - Service: Andrea ST Filters Service (AESTFilters) - Unknown owner - C:\Windows\System32\DriverStore\FileRepository\stwrt64.inf_d14bcbef\AESTSr64.exe (file missing)
O23 - Service: @%SystemRoot%\system32\Alg.exe,-112 (ALG) - Unknown owner - C:\Windows\System32\alg.exe (file missing)
O23 - Service: ##Id_String1.6844F930_1628_4223_B5CC_5BB94B879762## (Bonjour Service) - Apple Computer, Inc. - C:\Program Files (x86)\Bonjour\mDNSResponder.exe
O23 - Service: @dfsrres.dll,-101 (DFSR) - Unknown owner - C:\Windows\system32\DFSR.exe (file missing)
O23 - Service: Dock Login Service (DockLoginService) - Stardock Corporation - C:\Program Files\Dell\DellDock\DockLogin.exe
O23 - Service: FLEXnet Licensing Service - Macrovision Europe Ltd. - C:\Program Files (x86)\Common Files\Macrovision Shared\FLEXnet Publisher\FNPLicensingService.exe
O23 - Service: FlipShare Service - Unknown owner - C:\Program Files (x86)\Pure Digital Technologies\FlipShare\FlipShareService.exe
O23 - Service: Intel(R) Matrix Storage Event Monitor (IAANTMON) - Intel Corporation - C:\Program Files (x86)\Intel\Intel Matrix Storage Manager\IAANTMon.exe
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files (x86)\Common Files\InstallShield\Driver\11\Intel 32\IDriverT.exe
O23 - Service: @keyiso.dll,-100 (KeyIso) - Unknown owner - C:\Windows\system32\lsass.exe (file missing)
O23 - Service: McAfee SiteAdvisor Service - Unknown owner - C:\Program Files (x86)\McAfee\SiteAdvisor\McSACore.exe
O23 - Service: McAfee Services (mcmscsvc) - McAfee, Inc. - C:\PROGRA~2\McAfee\MSC\mcmscsvc.exe
O23 - Service: McAfee Network Agent (McNASvc) - McAfee, Inc. - c:\PROGRA~2\COMMON~1\mcafee\mna\mcnasvc.exe
O23 - Service: McAfee Scanner (McODS) - McAfee, Inc. - C:\PROGRA~1\McAfee\VIRUSS~1\mcods.exe
O23 - Service: McAfee Proxy Service (McProxy) - McAfee, Inc. - c:\PROGRA~2\COMMON~1\mcafee\mcproxy\mcproxy.exe
O23 - Service: McAfee Real-time Scanner (McShield) - McAfee, Inc. - C:\PROGRA~1\McAfee\VIRUSS~1\mcshield.exe
O23 - Service: McAfee SystemGuards (McSysmon) - McAfee, Inc. - C:\PROGRA~2\McAfee\VIRUSS~1\mcsysmon.exe
O23 - Service: McAfee Personal Firewall Service (MpfService) - McAfee, Inc. - C:\Program Files (x86)\McAfee\MPF\MPFSrv.exe
O23 - Service: @comres.dll,-2797 (MSDTC) - Unknown owner - C:\Windows\System32\msdtc.exe (file missing)
O23 - Service: McAfee Anti-Spam Service (MSK80Service) - McAfee, Inc. - C:\Program Files (x86)\McAfee\MSK\MskSrver.exe
O23 - Service: @%SystemRoot%\System32\netlogon.dll,-102 (Netlogon) - Unknown owner - C:\Windows\system32\lsass.exe (file missing)
O23 - Service: @%systemroot%\system32\psbase.dll,-300 (ProtectedStorage) - Unknown owner - C:\Windows\system32\lsass.exe (file missing)
O23 - Service: @%systemroot%\system32\Locator.exe,-2 (RpcLocator) - Unknown owner - C:\Windows\system32\locator.exe (file missing)
O23 - Service: @%SystemRoot%\system32\samsrv.dll,-1 (SamSs) - Unknown owner - C:\Windows\system32\lsass.exe (file missing)
O23 - Service: @%SystemRoot%\system32\SLsvc.exe,-101 (slsvc) - Unknown owner - C:\Windows\system32\SLsvc.exe (file missing)
O23 - Service: @%SystemRoot%\system32\snmptrap.exe,-3 (SNMPTRAP) - Unknown owner - C:\Windows\System32\snmptrap.exe (file missing)
O23 - Service: @%systemroot%\system32\spoolsv.exe,-1 (Spooler) - Unknown owner - C:\Windows\System32\spoolsv.exe (file missing)
O23 - Service: Audio Service (STacSV) - Unknown owner - C:\Windows\System32\DriverStore\FileRepository\stwrt64.inf_d14bcbef\STacSV64.exe (file missing)
O23 - Service: stllssvr - MicroVision Development, Inc. - C:\Program Files (x86)\Common Files\SureThing Shared\stllssvr.exe
O23 - Service: @%SystemRoot%\system32\ui0detect.exe,-101 (UI0Detect) - Unknown owner - C:\Windows\system32\UI0Detect.exe (file missing)
O23 - Service: @%SystemRoot%\system32\vds.exe,-100 (vds) - Unknown owner - C:\Windows\System32\vds.exe (file missing)
O23 - Service: @%systemroot%\system32\vssvc.exe,-102 (VSS) - Unknown owner - C:\Windows\system32\vssvc.exe (file missing)
O23 - Service: Dell Wireless WLAN Tray Service (wltrysvc) - Unknown owner - C:\Windows\System32\WLTRYSVC.EXE (file missing)
O23 - Service: @%Systemroot%\system32\wbem\wmiapsrv.exe,-110 (wmiApSrv) - Unknown owner - C:\Windows\system32\wbem\WmiApSrv.exe (file missing)
O23 - Service: @%ProgramFiles%\Windows Media Player\wmpnetwk.exe,-101 (WMPNetworkSvc) - Unknown owner - C:\Program Files (x86)\Windows Media Player\wmpnetwk.exe (file missing)
O23 - Service: Marvell Yukon Service (yksvc) - Unknown owner - RUNDLL32.EXE (file missing)
--
End of file - 8789 bytes
