Can't even get Hijackthis to work

[wise]

Problems with Google redirect and inability to scan computer

Mcafee, combofix, malwarebytes and hjackthis stops or shuts down when trying to run scan.

I tried running HijackThis in SafeMode, I click the Scan and Save Log File button, it starts to scan then program shuts down and gives me the error "Windows cannot access the specified device, path, or file. You may not have the appropriate permissions to access them."

When I don't run in safemode I get popups that look like security programs and the dektop background has changed saying I have a virus!

Please help

[NonSuch]

You may be having difficulty running certain programs, including HijackThis, due to the infection or infections currently residing on your computer. However, in order for us to help you it is necessary that you provide us with a HijackThis log, and it is possible you may be able to trick the malware into letting you do this. First, uninstall your current copy of HijackThis. Next, download HijackThis to a clean computer, then rename it from HijackThis.exe to any other name you want, using an .exe extension, for example... YourLastName.exe. Once you have done that, burn it to a CD (preferable to using a flash drive that may easily become infected) then transfer the renamed file to the infected computer and run a scan, then start a new topic and include your HijackThis log.

Please follow the guideline at the link below to start a new topic and post your HijackThis log. If you are unable to create and post a HijackThis log, then your only option may be to reformat your computer and reinstall the operating system.

This topic is now closed. Please start a new topic by following the HijackThis Guideline posted here, just be certain to rename HijackThis: >Guideline for posting your HijackThis log<